NAD+ Supplements: A Guide to Choosing Products Safely
Explore what NAD+ supplements are, how they compare to other NAD products, and what to know about potential benefits, dosing, and safety.
- NAD+ supplements may help support overall wellness and energy, but individual responses may vary.
- Many healthy individuals tolerate NAD+ supplements well, though some individuals may experience side effects such as nausea, digestive discomfort, or headaches.
- When choosing a supplement, always check for third-party testing, GMP certification, and transparent labeling.
- Avoid supplements that make exaggerated claims or don’t disclose ingredient amounts.
- Always discuss your options with a licensed healthcare provider before starting any new supplement, especially if you have existing health conditions.
This information is provided for educational purposes only and should not be considered medical advice, diagnosis, or treatment. It’s important to always consult a qualified healthcare professional before starting any new supplement or therapy. Dietary supplements, including NAD+ supplements, are not FDA-approved and should never be used to treat, cure, or prevent any disease.
NAD+ Supplement Benefits
If you’ve been exploring ways to support your energy, focus, or overall vitality, you’ve probably come across NAD+ supplements. And you’ve probably heard all the hype. But what can you actually expect? And are these supplements safe to take?
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every cell of your body. It plays a role in energy production, DNA maintenance, and cellular function. As you age, your natural NAD+ levels tend to decline, and many people, therefore, turn to supplements.
However, individual results vary, and supplements are not guaranteed to produce specific outcomes. So, should you take them?
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Are NAD+ Supplements Safe?
For many healthy adults, NAD+ supplements are generally considered safe when used as directed. However, like any supplement, they’re not without potential risks—and quality always matters.
Because dietary supplements aren’t regulated as strictly as prescription medications, the purity and potency of NAD+ supplements can vary significantly between brands. Choosing a reputable manufacturer that follows good manufacturing practices (GMP) and provides third-party testing is an important step in minimizing your risk.
Some people may experience mild side effects, particularly when first starting NAD+ supplements or when taking higher doses. These can include:
- Nausea
- Headache
- Fatigue
- Digestive discomfort
- Diarrhea
- Stomach cramping
- Flushing or warmth
Yet, these effects are usually temporary and often subside as the body adjusts.
Who Shouldn't Take NAD+ Supplements?
NAD+ supplements aren’t right for everyone. Individuals who are pregnant or breastfeeding should avoid these supplements due to a lack of safety data in these populations. Individuals managing chronic health conditions—particularly liver or kidney issues—should also consult a healthcare provider before starting any NAD+ regimen.
If you’re currently taking medications, it’s important to discuss potential interactions with your doctor. And because long-term safety data is still limited, anyone considering extended use should do so under medical guidance.
When in doubt, talk with a licensed healthcare provider to determine whether NAD+ supplements make sense for you, your health, and your goals.
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How to Choose Your Supplements Safely
With so many products on the market, knowing what to look for—and what to avoid—can help you make a more informed choice and decide what’s best for you. Here’s what to consider when selecting an NAD+ supplement.
Look for Third-Party Testing
Third-party testing means an independent lab has tested the product’s contents, purity, and potency. This is one of the most reliable ways to ensure you’re getting what's actually on the label. Look for certifications from organizations, such as NSF International, USP, or ConsumerLab.
Check for GMP Certification
Good Manufacturing Practices (GMP) certification indicates that a product was produced in a facility that meets quality and safety standards. Supplements made in GMP-certified facilities are less likely to contain contaminants or inconsistencies in dosage.
Choose the Right Form for You
NAD+ supplements come in several forms, including capsules, powders, sublingual tablets, and nasal sprays. Each has different absorption rates and convenience factors to consider. For instance, if you’re always on the go, capsules or powder may make the most sense.
Ultimately, it’s important to consider which form fits best with your lifestyle and preferences.
Check What’s on the Label
A quality supplement should have a clear, transparent label that lists all active ingredients and their amounts. It’s wise to avoid products with proprietary blends that don’t disclose specific dosages, as well as those with unnecessary fillers, artificial additives, or ingredients you don’t recognize.
Research the Brand
Not every supplement company holds itself to the same standards. So, make sure to look for brands with a solid reputation, transparent sourcing practices, and accessible customer support. Additionally, checking reviews and looking into how long a company has been in business can also provide helpful context.
If you want an NAD+ supplement you can feel confident about, Eden is a great choice. You get clear, easy-to-understand product details and a quality-first approach—so you can spend less time guessing and more time choosing what fits your routine.
Be Wary of Unrealistic or Over-the-Top Claims
If a product promises to reverse aging, cure disease, or deliver dramatic results overnight, consider this a red flag.
At the end of the day, reputable brands focus on what NAD+ may support instead of making exaggerated or unsupported claims. The rule of thumb: Steer clear of marketing that sounds too good to be true!
Consult a Licensed Healthcare Provider
Before starting any new supplement, it’s always a good idea to check in with a licensed healthcare provider—especially if you have existing health conditions or are taking other medications. They can help you determine if NAD+ supplement makes sense for you and what product or dose may be suitable for your individual needs.
Final Thoughts
With so many NAD+ supplements available, choosing the right one can be overwhelming. But taking the time to evaluate quality, transparency, and safety is important, especially when it comes to your overall health and safety.
Focus on brands that prioritize third-party testing, GMP certification, and clear labeling. But be cautious of products making bold claims. And don’t hesitate to ask questions or do your research before buying. Ultimately, consulting a healthcare provider is the best way to ensure any supplement you choose aligns with your individual health needs and goals.
Disclaimer: The FDA does not approve compounded medications for safety, quality, or manufacturing. Prescriptions and a medical evaluation are required for certain products. The information provided on this blog is for general informational purposes only. It is not intended as a substitute for professional advice from a qualified healthcare professional and should not be relied upon as personal health advice. The information contained in this blog is not meant to diagnose, treat, cure, or prevent any disease. Readers are advised to consult with a qualified healthcare professional for any medical concerns, including side effects. Use of this blog's information is at your own risk. The blog owner is not responsible for any adverse effects or consequences resulting from the use of any suggestions or information provided in this blog.
Eden is not a medical provider. Eden connects individuals with independent licensed healthcare providers who independently evaluate each patient to determine whether a prescription treatment program is appropriate. All prescriptions are written at the sole discretion of the licensed provider. Medications are filled by state-licensed pharmacies. Please consult a licensed healthcare provider before making any medical decisions.
Frequently asked questions
NAD+ supplements may help support cellular energy production and overall wellness, though individual results vary. More research is needed to fully understand their long-term effectiveness.
For most healthy adults, NAD+ supplements are generally well-tolerated. However, side effects, such as nausea or headaches, can occur, and individuals with certain health conditions should consult a licensed healthcare provider beforehand.
This ultimately depends on your preferences and goals. For example, capsules and powders are often more convenient for daily use.
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References
Conlon N. J. (2022). The Role of NAD+ in Regenerative Medicine. Plastic and reconstructive surgery, 150(4 Suppl ), 41S–48S. https://doi.org/10.1097/PRS.0000000000009673
ConsumerLab.com. (n.d.). ConsumerLab.com. https://www.consumerlab.com/
Dietary Supplement Manufacturing - USP Verified Mark | USP. (n.d.). https://www.usp.org/verification-services/verified-mark
Gindri, I. M., Ferrari, G., Pinto, L. P. S., Bicca, J., Dos Santos, I. K., Dallacosta, D., & Roesler, C. R. M. (2024). Evaluation of safety and effectiveness of NAD in different clinical conditions: a systematic review. American journal of physiology. Endocrinology and metabolism, 326(4), E417–E427. https://doi.org/10.1152/ajpendo.00242.2023
NSF. (n.d.). nsf.org. https://www.nsf.org/
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