NAD Injections: Everything You Need to Know

What is an NAD injection?

Appearing in IV lounges, longevity clinics, and various social media posts, NAD injections have been making the rounds. And while they may sound like just another buzzword, there are a few reasons why they’ve caught so much attention.

NAD+, short for nicotinamide adenine dinucleotide, is a coenzyme found in every cell of your body. It plays an important role in energy production, DNA repair, and overall cellular health. 

But NAD+ levels naturally decline as you age. By the time you hit your 40s or 50s, your body may have less NAD+ than it did in your younger years. 

NAD injections are a way to deliver NAD+ directly into your body—typically through a subcutaneous (under the skin) or intramuscular injection. Oral supplements have to go through your digestive system, where your body may not absorb all of it. Injections skip that step.

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NAD Injections Benefits 

Here are the potential benefits of NAD shots.

May Increase Energy Levels

NAD+ supports the cellular processes that produce ATP, the body’s primary energy source. Thus, lower NAD+ levels may affect this process and may be associated with reduced energy. 

NAD injections are being explored in clinical and wellness settings as a way to administer NAD+ under medical supervision. As such, researchers continue to study how NAD+ availability relates to and may impact cellular energy processes.

May Improve Mental Clarity and Focus

As noted above, NAD+ supports brain energy metabolism and enzymes involved in neuronal function and cellular repair. Because the brain has high energy demands, reduced NAD+ availability may affect cognitive efficiency and contribute to symptoms often described as “brain fog.” 

NAD+ has been and is being studied in relation to cellular processes involved in brain energy metabolism. In fact, some research explores NAD+ in relation to neuroinflammatory pathways. However, results vary from person to person, and research is still evolving.

May Contribute to Cellular Repair and Support Healthy Aging

NAD+ is associated with proteins called sirtuins, which are studied in relation to the cellular stress response. As such, researchers are exploring how NAD+ availability relates to cellular maintenance over time.

May Support Metabolism

NAD+ is involved in the metabolic processes that turn nutrients into usable energy. Thus, emerging research will help clarify NAD’s exact role in metabolic function and overall metabolic processes.

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NAD+ Injection Risks & Side Effects

Like any therapy, getting an NAD shot may come with potential side effects. However, most are mild and tend to resolve quickly as your body adjusts.

The most common side effects include:

• Redness, soreness, or bruising at the injection site
• Mild nausea
• Flushing or a warm sensation
• Headache
• Lightheadedness or dizziness
• Fatigue shortly after the injection
• Cramping or discomfort

These reactions are typically short-lived and often depend on the dosage and how quickly the NAD+ is administered.  

With that said, NAD injections aren’t right for everyone. If you have underlying health conditions or are taking other medications, it’s important to talk with a healthcare provider before starting any NAD therapy. 

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Final Thoughts

NAD injections have gained attention for their potential role in wellness and longevity. But it’s worth noting that research is still catching up to the hype.

If you’re considering NAD therapy, the best first step is talking with a healthcare provider who can evaluate your individual needs and help you decide if it’s right for you.

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