How GLP-1 Medications Are Prescribed

What Are GLP-1 Medications?

GLP-1 receptor agonists are a class of medications that mimic the action of glucagon-like peptide-1, a natural hormone that plays a role in insulin secretion, blood sugar regulation, digestion, and appetite signaling.

While initially developed for the management of Type 2 diabetes, certain GLP-1 medications have since received FDA approval for chronic weight management in adults with obesity or overweight and specific health conditions.

These medications are not available over-the-counter. They require a prescription following a medical evaluation by a licensed healthcare provider.

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Who Can Prescribe GLP-1 Medications?

Only licensed healthcare providers, such as physicians, nurse practitioners, or physician assistants, are authorized to prescribe GLP-1 receptor agonists. These professionals assess each patient’s health history, current medications, lab values, and treatment goals before determining if a GLP-1 medication is appropriate.

On the Eden platform, patients are matched with independent, licensed healthcare providers who review this information during a secure, virtual consultation.

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What Happens During a GLP-1 Evaluation?

Before a GLP-1 medication can be prescribed, patients undergo a comprehensive assessment. A provider may ask about:

• Personal and family medical history
  
• Current medications or supplements
  
• Blood pressure, weight, and metabolic lab markers
  
• Previous experiences with other treatments
  
• Daily habits, including eating patterns, activity level, and lifestyle
  
  

This process helps the provider determine whether a GLP-1 medication is appropriate, and which formulation (oral or injectable) may best suit the patient’s needs.

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What Factors Influence Eligibility?

Not everyone is a candidate for GLP-1 therapy. A licensed provider will consider a range of medical factors, including:

• BMI and metabolic indicators
  
• Presence of conditions such as Type 2 diabetes or insulin resistance
  
• History of pancreatitis or gallbladder disease
  
• Gastrointestinal tolerance and medication adherence ability
  
• Interactions with other prescribed medications
  
  

These medications are only prescribed when the potential benefits outweigh the risks, and only after confirming no contraindications are present.

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How Do Providers Decide on the Formulation and Dose?

GLP-1 medications are available in various forms, most commonly as injectables, and in some cases, as oral formulations (such as high-dose oral semaglutide). Dosing typically begins at a lower amount and is gradually increased over time, which may improve tolerability and reduce the likelihood of side effects.

The provider selects the form and dosing schedule based on:

• The patient’s medical profile
  
• Prior response to medications
  
• Preferences around injection vs. oral administration
  
• Insurance coverage and pharmacy access
  
  

Example: Rybelsus® is an oral GLP-1 approved for daily use, while Ozempic®, Wegovy®, and Saxenda® are injectables approved for specific conditions.

Eden does not manufacture or dispense medications, but it facilitates care by connecting patients with independent, licensed providers who determine the best course of action.

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Where Do the Medications Come From?

Once a licensed provider determines that a GLP-1 medication is appropriate and prescribes it, the prescription is sent to a state-licensed pharmacy for fulfillment.

Depending on availability and patient-specific factors, providers may work with:

• Traditional retail pharmacies
  
• Mail-order pharmacies
  
• State-licensed compounding pharmacies, when clinically appropriate and legally permitted
  
  

Regardless of the source, all medications are dispensed under the supervision of a licensed pharmacist and shipped directly to the patient when possible.

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Is Follow-Up Required?

Yes. GLP-1 medications typically require ongoing monitoring to ensure safety, manage side effects, and assess progress toward treatment goals. Licensed providers may schedule follow-up appointments to:

• Adjust dosing
  
• Review lab work or biometrics
  
• Address side effects or new symptoms
  
• Evaluate long-term outcomes
  
  

This continuity of care helps ensure that the treatment remains safe, effective, and aligned with each patient's evolving needs.

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Conclusion

GLP-1 medications are only prescribed after a thorough evaluation by a licensed healthcare provider. The process involves a comprehensive review of your health history, lifestyle, and treatment goals, followed by ongoing monitoring to support your progress.

Eden simplifies access by connecting you to providers who understand the nuances of metabolic care and can help you determine whether GLP-1 treatment is appropriate for your individual needs.

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