Appetite loss on GLP-1s may lead to lower intake of essential nutrients. Learn how fiber and phytonutrient gaps happen, and how Gainful Daily Performance Greens may help.
GLP-1 medications like semaglutide and tirzepatide have brought powerful change to metabolic health treatment. But as many people start to see results, a quieter issue emerges: nutrient shortfalls from eating less.
Reduced appetite and slower digestion may result in fewer total calories, which can lead to lower fiber intake, fewer fruits and vegetables, and reduced phytonutrient diversity. Over time, this may impact digestion, energy levels, and overall wellness.
In this article, we’ll explore the nutrition gaps commonly seen on GLP-1s and how strategies like fiber inclusion and plant-based nutrient support (including products like Gainful Daily Performance Greens) may help you stay balanced while your appetite is reduced.
One of the main mechanisms of GLP-1 medications is appetite reduction. While this supports weight loss and improved metabolic markers, it often leads to unintended changes in your overall nutrient intake.
When you're eating less volume overall, getting these benefits from food alone becomes more challenging.
According to a joint 2025 advisory published in the American Journal of Clinical Nutrition, reduced intake of fiber and nutrient-dense plant foods is one of the most common nutrition concerns during GLP-1 therapy.
Low fiber and phytonutrient intake may:
That’s why it’s so important to be proactive, even if your appetite is low.
You don’t need to overhaul your diet, but small steps can help bridge nutrient gaps and support how you feel.
Choose high-density produce like spinach, avocado, broccoli, and berries. Even a half-cup of greens can provide meaningful amounts of micronutrients and fiber.
When eating large salads or smoothies isn’t realistic, a greens supplement may offer phytonutrient support in an easy-to-digest format.
Signs of low fiber or phytonutrient intake may include constipation, dull skin, poor digestion, or lower energy. These symptoms may indicate your body needs more variety.
Instead of large meals, incorporate small, nutrient-dense additions—like half a scoop of greens powder mid-morning or a veggie-based broth at dinner.
{{primary-cta}}
Gainful Daily Performance Greens is formulated for individuals who may be eating less during GLP-1 therapy but still want to support comprehensive daily nutrition.
While supplements can’t replace whole foods, Gainful Daily Performance Greens offers a convenient way to help support your intake of fiber and plant-based nutrients when overall food consumption is reduced.
If you’re feeling unusually fatigued, constipated, or lacking energy on GLP-1 therapy, it may be related to low micronutrient or fiber intake. A licensed provider can help assess whether dietary changes, hydration support, or supplement strategies may be beneficial.
Eden connects you with independent, licensed healthcare providers who can evaluate your needs and monitor your nutritional status while on GLP-1 treatment.
GLP-1s reduce appetite, but that doesn’t mean your body needs fewer nutrients. In fact, getting enough fiber, phytonutrients, and supportive compounds becomes even more important as your food volume drops.
Simple changes, like including small portions of plants, drinking water with electrolytes, or adding a scoop of Gainful Daily Performance Greens, can have a big impact on how you feel and how your body responds to treatment.
With Eden and Gainful, you don’t have to navigate this alone. You have science-backed support to help you feel your best, one step at a time.
{{primary-cta}}
Disclaimer: The FDA does not approve compounded medications for safety, quality, or manufacturing. Prescriptions and a medical evaluation are required for certain products. The information provided on this blog is for general informational purposes only. It is not intended as a substitute for professional advice from a qualified healthcare professional and should not be relied upon as personal health advice. The information contained in this blog is not meant to diagnose, treat, cure, or prevent any disease. Readers are advised to consult with a qualified healthcare professional for any medical concerns, including side effects. Use of this blog's information is at your own risk. The blog owner is not responsible for any adverse effects or consequences resulting from the use of any suggestions or information provided in this blog.
Eden is not a medical provider. Eden connects individuals with independent licensed healthcare providers who independently evaluate each patient to determine whether a prescription treatment program is appropriate. All prescriptions are written at the sole discretion of the licensed provider. Medications are filled by state-licensed pharmacies. Please consult a licensed healthcare provider before making any medical decisions.
Mozaffarian, D., et al. (2025). Nutritional priorities to support GLP-1 therapy for obesity: A joint advisory. American Journal of Clinical Nutrition. https://doi.org/10.1016/j.ajcnut.2025.04.023
