Key Differences: Jardiance vs. Metformin
Feature |
Metformin |
Jardiance |
FDA-approved for type 2 diabetes |
Yes |
Yes |
FDA-approved for heart failure |
No |
Yes |
May be prescribed for metabolic uses by a licensed healthcare provider |
Yes (e.g., PCOS, prediabetes) |
Less common |
Primary mechanism |
Reduces liver glucose production |
Promotes glucose excretion via urine |
Risk of hypoglycemia |
Low |
Low, slightly higher with insulin |
Gastrointestinal side effects |
Common |
Rare |
Risk of urinary tract infection |
Low |
Moderate |
Cardiovascular indications |
Modest |
Strong (FDA-approved for heart failure) |
Reported weight impact in Studies |
Mild in some individuals |
Mild to moderate in some studies |
What About Weight Loss?
Neither Metformin nor Jardiance is approved for weight loss. Some individuals may report changes in weight while taking these medications, but results vary. A licensed healthcare provider should guide any use outside of FDA-approved indications.
Q: Why might a provider consider Metformin?
A: Metformin is one of the most commonly prescribed medications for type 2 diabetes and may be prescribed by licensed healthcare providers for individuals showing signs of insulin resistance. Some providers may explore it as an option when evaluating care plans for qualifying individuals. Any decision about medication should be made by a licensed provider based on a full clinical evaluation.
Who Might Be a Candidate for Each?
Metformin may be a discussed option by a provider in situations where a patient:
- Has been diagnosed with insulin resistance, PCOS, or prediabetes
- Is exploring non-injectable options for glucose regulation
- Is looking to manage glucose levels
Jardiance may be discussed by a specialist if a patient:
- Has type 2 diabetes and cardiovascular disease
- Has not reached glucose targets with other medications
- Is under the care of a specialist (e.g., cardiologist or endocrinologist)
How Eden Uses Metformin
Eden’s provider-guided MedKits may include Metformin for eligible members post-assessment by a licensed healthcare provider. These kits are prescribed by licensed providers and may include:
- Gradual titration of Metformin ER 500 mg
- Nutrient formulations recommended by providers to support digestive tolerance
- Monthly check-ins to assess tolerability and adherence
Disclaimer
Metformin and Jardiance are FDA-approved for the treatment of type 2 diabetes. Jardiance is also approved for reducing the risk of cardiovascular death in adults with heart failure. Eden does not produce, dispense, or prescribe medications. All prescriptions are written by independent licensed providers and filled by state-licensed pharmacies. A clinical assessment is required to determine eligibility. Individual experiences may vary.
Please note that compounded medications are not reviewed by the FDA for safety, quality, or efficacy.
Curious if Metformin Could Support Your Metabolic Goals?
Wondering if Metformin might be right for you?
Take Eden’s free provider-guided assessment to explore your options for glucose management and metabolic care.