Learn what emerging research says about low dose naltrexone (LDN) for supporting appetite awareness and behavior consistency. Eden-affiliated providers may include LDN in personalized, provider-directed care plans for eligible adults.
*Structure-function claims are based on observed mechanisms; not intended to treat or cure disease.
LDN refers to naltrexone prescribed at lower doses (1.5–4.5 mg/day)—a fraction of the 50 mg standard used for opioid and alcohol dependency.
At low doses, it's thought to:
Reference: Younger et al., 2014 – Clinical Rheumatology Examined LDN’s impact on endorphins and inflammatory pathways in chronic pain populations.
These mechanisms may support efforts related to weight management, particularly when emotional or habitual patterns are a factor. However, controlled research is still needed.
In FDA-approved Contrave®, naltrexone is combined with bupropion. However, the clinical effects cannot be attributed to LDN alone.
Greenway et al., 2010 – The Lancet
Licensed providers working with Eden may recommend LDN as part of a provider-directed care strategy to support behavioral or emotional wellness.
These blends may support:
Other active ingredients may include:
*These uses are not FDA-approved. Medications are prescribed at the discretion of licensed providers based on individual clinical assessment.
Q: Will LDN make me lose weight?
A: LDN is not a weight loss drug and is not FDA-approved for that purpose. However, for some people, it may help address underlying behavioral patterns that contribute to weight challenges. Eden providers focus on mood and habit support, not guaranteed weight outcomes.
While formal clinical studies are ongoing, Eden members have reported:
Possible early side effects:
Low-dose naltrexone is not FDA-approved for weight loss, cravings, or appetite control. Eden offers LDN in off-label, provider-directed compounded formulations. Any outcomes mentioned are based on small-scale observations and individual reports—not guaranteed or FDA-validated. Eden does not manufacture or dispense medications; all prescriptions are filled by third-party, state-licensed compounding pharmacies.
Take Eden’s free provider-guided assessment to explore if you're a candidate for care plans that may support behavior change, motivation, or appetite awareness.
Disclaimer: The FDA does not approve compounded medications for safety, quality, or manufacturing. Prescriptions and a medical evaluation are required for certain products. The information provided on this blog is for general informational purposes only. It is not intended as a substitute for professional advice from a qualified healthcare professional and should not be relied upon as personal health advice. The information contained in this blog is not meant to diagnose, treat, cure, or prevent any disease. Readers are advised to consult with a qualified healthcare professional for any medical concerns, including side effects. Use of this blog's information is at your own risk. The blog owner is not responsible for any adverse effects or consequences resulting from the use of any suggestions or information provided in this blog.
