How to Know if Metformin is Working: 5 Signs to Watch For

What Metformin Does—And What It Doesn’t

Metformin is a prescribed medication for metabolic health, but how do you know if it’s actually doing its job?

Whether you're exploring Metformin through a provider for insulin resistance, PCOS, or as part of a broader wellness reset, it’s helpful to know what to look for. Here are five subtle but meaningful signs Metformin may be working for you: 

1. More Stable Energy After Meals

Oftentimes, those with metabolic conditions may feel sluggish after meals or experience mid-afternoon crashes, and now find themselves with steadier energy; it could mean your body is handling glucose more effectively..

Metformin works by reducing glucose production in the liver and improving how your muscles respond to insulin. While you might not “feel” it directly, your energy levels may be telling a different story.

Please note that you should periodically check in with a healthcare provider to determine changes in medical signs as you start any new medications. 

2. Fewer Cravings or Appetite Changes

Metformin is not an appetite suppressant. However, some people may report a reduced urge to snack, especially on sugar or carbs. This may be related to better blood sugar stability.

Reminder: Metformin is not FDA-approved for weight loss and should not be used for this purpose alone, unless directed by a provider.

If your provider recommends it, you may be starting on the Metformin MedKit ↗, Eden’s prescription-based approach with built-in provider support. Please note that you must first be assessed by a healthcare provider who will determine whether or not you are an eligible candidate for the medication. 

3. Lab Improvements Over Time

Signs that Metformin is working may come from your lab results. You may notice:

• Lower fasting glucose
  
• Lower HbA1c (your 3-month average blood sugar)
  
• Improved fasting insulin levels
  
  

These changes typically appear within 2-3 months, so don’t expect an overnight difference.

4. Digestive Discomfort That Eventually Fades

If you're experiencing nausea, bloating, or loose stools early on, that’s not unusual. These side effects are common and generally improve over time. Please consult your healthcare provider if you feel that any symptoms are not improving.

Eden’s providers often recommend starting low and titrating slowly, a common strategy in the Eden MedKit program.

5. Feeling More in Control of Food Choices

Some Eden members describe feeling more “present” and aware of hunger signals after starting Metformin. This may be influenced by glucose stability or gut-brain signaling.

If appetite regulation and energy improvement are part of your goals, your provider might suggest pairing Metformin with Everyday+ nutrients like inositol and B12.
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When to Talk to a Provider

If you're unsure whether Metformin is helping, the best step is to schedule a check-in with your provider. Bloodwork and symptom tracking may help guide next steps, including dose adjustments or supportive add-ons.

You can also start a provider assessment online to see if Metformin is right for your plan.
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Eden’s Role

Eden doesn’t manufacture or dispense medications. Instead, we connect patients with licensed providers who may prescribe Metformin off-label when appropriate.

Our Metformin MedKits include:

• Provider-guided dosing
  
• Free home delivery
  
• Supportive resources and refills every 90 days
  
  
  

Disclaimer

Metformin is not FDA-approved for weight loss. Eden does not produce, compound, or dispense medications. Please note that compounded medications are not reviewed by the FDA for quality, safety or efficacy. Individual results may vary.
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Curious whether Metformin might support your energy or blood sugar goals?

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