Exploring Alternatives to Semaglutide: Key Information to Discuss with a Licensed Healthcare Provider

What Is Semaglutide?

Semaglutide belongs to a class of prescription medications known as GLP-1 receptor agonists. These medications mimic the action of a natural hormone involved in regulating appetite and digestion.

FDA-approved forms of semaglutide include injectable and oral options marketed under brand names like Ozempic®, Wegovy®, and Rybelsus®. Each is approved for specific indications, which patients can review with a licensed healthcare provider.

‍

FDA-Approved Prescription Options to Discuss with a Licensed Healthcare Provider

Below are FDA-approved medications that patients may wish to discuss with their licensed healthcare provider. Each medication has unique characteristics and approval indications and may have varying effects depending on individual health needs.

‍

1. Tirzepatide (Zepbound® / Mounjaro®)

Tirzepatide is a dual GIP and GLP-1 receptor agonist. FDA-approved under the brand names Mounjaro® for type 2 diabetes and as Zepbound® for chronic weight management.

Patients should consult a licensed healthcare provider to determine whether this medication aligns with their treatment goals.

2. Rybelsus® (Oral Semaglutide)

Rybelsus® is currently the only FDA-approved oral formulation of semaglutide. It is indicated for the treatment of type 2 diabetes and may be considered for individuals seeking non-injectable treatment options.

3. Wegovy®

Wegovy® is an injectable prescription medication that contains semaglutide and is FDA-approved for chronic weight management in adults with obesity or those who are overweight and have at least one weight-related health condition. It is typically prescribed as part of a comprehensive treatment plan that includes lifestyle modifications and ongoing supervision from a licensed healthcare provider.

4. Dulaglutide (Trulicity®)

Dulaglutide (Trulicity®) is a once-weekly GLP-1 receptor agonist indicated for the treatment of type 2 diabetes. It may also reduce cardiovascular risk in certain patients.

A licensed healthcare provider may help determine whether this medication fits within your overall treatment plan.

5. Liraglutide (Saxenda® / Victoza®)

Liraglutide is available in two FDA-approved formulations: Victoza®, for the treatment of type 2 diabetes, and Saxenda®, for chronic weight management.

Patients should consult a licensed healthcare provider to assess which, if any, of these options may be appropriate based on their medical history and health goals.

‍

What About Over-the-Counter Supplements?

Some supplements, such as berberine or cinnamon, are marketed for general wellness or metabolic support. However, these products are not FDA-approved for the treatment of obesity or type 2 diabetes, and their effectiveness has not been established in large-scale clinical trials.

Always consult a licensed healthcare provider before adding supplements to your care plan.

‍

Why try Eden?

Eden is a digital health platform that may help individuals connect with licensed healthcare providers who can evaluate whether GLP-1-based therapy may be appropriate based on each patient’s health history and goals. Through the Eden platform, licensed healthcare providers may:

• Review your medical history and treatment objectives
• Recommend appropriate prescription therapies
• Send prescriptions to state-licensed compounding pharmacies when medically appropriate

Ready to take the next step? Connect with an independent, licensed healthcare provider through Eden to discuss whether GLP-1-based treatment options may be appropriate for your needs.