Considering Alternatives to Semaglutide: Key Information to Review with Your Healthcare Provider

What Is Semaglutide?

Semaglutide belongs to a class of prescription medications known as GLP-1 receptor agonists. These medications mimic the action of a natural hormone involved in regulating appetite and digestion.

FDA-approved forms of semaglutide include injectable and oral options marketed under brand names like Ozempic®, Wegovy®, and Rybelsus®. These medications are not affiliated with Eden. Each is approved for specific indications, which patients can review with a licensed healthcare provider.

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FDA-Approved Prescription Options to Discuss with a Licensed Healthcare Provider

Below are FDA-approved medications that patients may wish to discuss with a licensed healthcare provider. Each medication has unique characteristics and approved uses, and potential effects can vary based on individual health history and provider evaluation..

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1. Tirzepatide (Zepbound® / Mounjaro®)

Tirzepatide is a dual GIP and GLP-1 receptor agonist. FDA-approved under the brand names Mounjaro® for type 2 diabetes and as Zepbound® for chronic weight management.

Individuals should speak with a licensed healthcare provider to determine whether this medication is appropriate based on their health history and medical evaluation.

2. Rybelsus® (Oral Semaglutide)

Rybelsus® is currently the only FDA-approved oral formulation of semaglutide. It is indicated for the treatment of type 2 diabetes. Individuals interested in non-injectable options should consult a licensed healthcare provider to determine whether this medication is appropriate for their health needs.

3. Wegovy®

Wegovy® is an injectable prescription medication that contains semaglutide and is FDA-approved for chronic weight management in adults with obesity or those who are overweight and have at least one weight-related health condition. It is often used alongside lifestyle changes under the supervision of a licensed healthcare provider who determines the most appropriate treatment approach for each individual.

4. Dulaglutide (Trulicity®)

Dulaglutide (Trulicity®) is a once-weekly GLP-1 receptor agonist indicated for the treatment of type 2 diabetes. It may also reduce cardiovascular risk in certain patients.

A licensed healthcare provider can determine whether this medication is appropriate based on your individual health profile and treatment needs.

5. Liraglutide (Saxenda® / Victoza®)

Liraglutide is available in two FDA-approved formulations: Victoza®, for the treatment of type 2 diabetes, and Saxenda®, for chronic weight management.

Individuals should consult a licensed healthcare provider to determine whether either medication is appropriate based on their health history and clinical evaluation.

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What About Over-the-Counter Supplements?

Some supplements, such as berberine or cinnamon, are marketed for general wellness or metabolic support. However, these products are not FDA-approved for the treatment of obesity or type 2 diabetes, and their effectiveness has not been established in large-scale clinical trials.

Always consult a licensed healthcare provider before adding supplements to your care plan.

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Why try Eden?

Eden is a digital health platform that may help individuals connect with licensed healthcare providers who can evaluate whether GLP-1-based therapy may be appropriate based on each patient’s health history and goals. Through the Eden platform, licensed healthcare providers may:

• Review your medical history and treatment objectives
• Determine whether prescription therapy is appropriate
• Send prescriptions to state-licensed compounding pharmacies when medically appropriate

Ready to take the next step? Connect with an independent, licensed healthcare provider through Eden to discuss whether GLP-1-based treatment options may be appropriate for your needs.