GLP-1 and 3-Month Weight Trends: What Patients Should Know

Learn how patients using GLP-1 therapy alongside lifestyle changes have experienced weight trends over 3 months. Explore how Eden connects patients with licensed healthcare providers for individualized care discussions.

Key takeaways
  • Some patients using GLP-1 receptor agonists under the care of a licensed provider and in combination with lifestyle changes have experienced gradual weight loss.
  • Clinical studies suggest 5–7% average weight reductions at 3 months among patients following prescribed protocols, though individual outcomes vary.
  • Factors like baseline BMI, dosing, adherence, and diet may influence weight management progress.
  • Regular communication with a licensed provider may help ensure safe and consistent use of prescribed therapies.

Please note that this article is not meant to be medical advice; please consult a licensed healthcare provider to determine best practices for your health. Results will vary from individual to individual - this is not meant to provide conclusive evidence for those on GLP-1 medications. Please consult with your licensed healthcare provider to understand the effects of GLP-1 medications on your health. Eden is not a pharmacy nor a medical provider.

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How GLP-1 May Promote Weight Management

GLP-1 receptor agonists, including medications like semaglutide, are designed to mimic the function of naturally occurring hormones involved in appetite and digestion.
In clinical settings, these medications have been studied for their potential to:

  • Slow gastric emptying
  • Increase feelings of fullness
  • Help reduce caloric intake
  • Support improved blood sugar management in people with type 2 diabetes

Some individuals with obesity may have impaired GLP-1 hormone function, and GLP-1 receptor agonists are one tool licensed healthcare providers may consider in managing appetite-related challenges.

Undergo a health assessment to determine whether or not you are an eligible candidate for GLP-1 medications with licensed healthcare providers you may connect with via the Eden platform.

Average Weight Loss After 3 Months on GLP-1

In peer-reviewed clinical and observational studies, some individuals using GLP-1 receptor agonists like semaglutide for weight management under the care of licensed providers have experienced meaningful weight changes.

Supported by Research

  • A 2024 study by Tzoulis et al. reported a median weight reduction of 6.6% (about 7.4 kg) over 3 months in adults with overweight and obesity who did not have type 2 diabetes.
  • Memon et al. (2024) found a mean weight loss of 5.81 kg in a mixed cohort, with consistent results regardless of diabetes status.
  • Lautenbach et al. (2022) observed a 6.0% weight reduction in post-bariatric patients continuing semaglutide.



Real-World Patient Experiences

Individuals who have used the Eden platform to connect with licensed healthcare providers have shared feedback about their experience accessing GLP-1 therapy:

  • Mandy G. lost 17 pounds in 9 weeks: “My cravings are gone, and I feel more energetic.”
  • Chelsea lost 25 pounds and cited Eden’s structured support as key to her progress.
  • Jeneece dropped over 15 pounds while managing high blood pressure and cholesterol.

These stories reflect personal experiences and should not be interpreted as typical or guaranteed results. Results may vary from individual to individual–please consult with your licensed healthcare provider to discuss your health. Eden does not provide medical care or make treatment decisions–our platform connects users with licensed healthcare providers who determine appropriate care based on individual health needs.

Explore patient-centered GLP-1 care via licensed healthcare providers via the Eden platform.

These stories reflect personal experiences and should not be interpreted as typical or guaranteed results. Eden does not provide medical care or make treatment decisions—our platform connects users with licensed healthcare providers who determine appropriate care based on individual health needs.

What May Influence Weight Changes During GLP-1 Therapy

1. Starting Weight and Body Mass Index (BMI)

Individuals with a higher baseline body weight may see more noticeable absolute weight changes, though percentage-based loss can vary widely.

2. Treatment Adherence

Following the prescribed medication schedule—including dose titration and injection timing—may contribute to more consistent outcomes, especially under medical supervision.

3. Lifestyle and Behavior

Licensed healthcare providers may recommend patients complement GLP-1 therapy with healthy daily habits such as:

  • Choosing lean proteins and fiber-rich foods
  • Staying well-hydrated (2.5–3 liters/day)
  • Engaging in regular movement, including walking and resistance training

These behaviors may help support weight management goals and promote general well-being, regardless of medication use.

What to Know About Goal-Setting in the First 3 Months

In some clinical studies, patients taking GLP-1 medications under medical supervision experienced weight reductions of approximately 5–7% within three months. While these results are not guaranteed and individual responses may vary, licensed healthcare providers have referenced this range as a general benchmark for early progress.

Rather than focusing solely on the scale, many licensed healthcare providers encourage patients to use the first 90 days to:

  • Establish consistent routines with medication and lifestyle
  • Build sustainable habits around nutrition and movement
  • Track progress using journals, apps, or check-ins with healthcare professionals

Rapid or extreme dietary restriction is not recommended and may lead to discomfort, side effects, or difficulty maintaining treatment over time.

Strategies That May Help You Stay on Track

While experiences with GLP-1 medications can vary widely, some patients working with licensed healthcare providers have found the following strategies helpful in maintaining healthy routines during the first few months:

  • Track food intake using a journal or mobile app to increase awareness of patterns and support consistency.
  • Follow your prescribed medication schedule as your licensed healthcare provider advises—avoid skipping or doubling doses.
  • Reduce ultra-processed foods and added sugars intake, and focus on nutrient-dense options.
  • Meet regularly with your licensed healthcare provider to review your experience, monitor your response, and adjust your plan as needed.

These lifestyle behaviors may help support broader wellness goals and improve adherence to your overall health plan.

Final Thoughts

GLP-1 receptor agonists like semaglutide have been studied for their potential role in supporting weight-related goals when used under the guidance of licensed healthcare providers. While individual results vary, some patients have reported changes in appetite, eating patterns, and weight when treatment is combined with sustainable lifestyle changes.

The first few months of any wellness journey often provide an opportunity to build healthy routines and establish consistency. Whether you're just getting started or exploring new options, working closely with a licensed healthcare provider who can evaluate your medical history and help determine the most appropriate path forward is important.

Eden is a digital platform that connects individuals with licensed providers to explore whether GLP-1-based care may be right for them.

This article is for educational purposes only and is not a substitute for professional medical advice. Always consult a licensed healthcare provider before beginning or changing any treatment plan.

Disclaimer: The FDA does not approve compounded medications for safety, quality, or manufacturing. Prescriptions and a medical evaluation are required for certain products. The information provided on this blog is for general informational purposes only. It is not intended as a substitute for professional advice from a qualified healthcare professional and should not be relied upon as personal health advice. The information contained in this blog is not meant to diagnose, treat, cure, or prevent any disease. Readers are advised to consult with a qualified healthcare professional for any medical concerns, including side effects. Use of this blog's information is at your own risk. The blog owner is not responsible for any adverse effects or consequences resulting from the use of any suggestions or information provided in this blog.

Frequently asked questions

Can I lose more than 10% of my weight in 3 months?

Some individuals in clinical studies have reported greater weight reductions, particularly those starting at a higher baseline BMI. However, outcomes vary widely and are influenced by factors like adherence, provider oversight, and lifestyle behaviors.

Is it safe to stop GLP-1 medications after reaching a goal?

Decisions about continuing or discontinuing treatment should be made with a licensed healthcare provider. Some individuals have reported weight regain after stopping treatment, which is one reason providers often take a personalized, phased approach.

Does exercise help while using GLP-1 therapy?

Physical activity can support general health and help preserve muscle mass during weight management. Many healthcare providers recommend combining movement with other lifestyle changes during any treatment program.

Are results from GLP-1 therapy permanent?

No. Long-term results depend on many factors, including continued lifestyle habits and medical guidance. For some individuals, GLP-1 medications are part of an ongoing health strategy.

Who is eligible for GLP-1 therapy?

GLP-1 receptor agonists may be prescribed to adults with a BMI of 30 or above, or 27+ with a weight-related condition, depending on licensed healthcare provider evaluation. Eden connects users with licensed healthcare providers who can determine eligibility based on a full review of personal health history.

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References