Benefits of Estrogen Replacement Therapy for Women

Learn how estrogen replacement therapy may help ease menopause symptoms and support wellness goals. Start your personalized evaluation with Eden today.

Key takeaways
  • Estrogen levels typically decline during menopause, which may lead to disruptive symptoms.
  • Estrogen replacement therapy may help reduce the intensity of hot flashes, night sweats, and sleep disturbances.
  • Some research suggests that estrogen therapy may support bone density, cardiovascular markers, and body composition when monitored by a qualified provider.
  • Available delivery methods include patches, creams, tablets, and vaginal applications.
  • Eden connects patients with licensed healthcare providers for convenient, personalized hormone therapy evaluations.

Estrogen plays a key role in women’s health throughout their reproductive years. As estrogen levels begin to decline during midlife, many women experience uncomfortable symptoms and changes that affect their overall quality of life.

Estrogen replacement therapy (ERT) is a physician-guided approach that may help support a more comfortable transition during menopause. For some women, it may offer more than just symptom relief, it may help them feel more balanced, energized, and empowered during this next chapter.

Eden is a digital health platform that connects women to licensed healthcare providers who specialize in hormone-related care. If you're experiencing symptoms related to perimenopause or menopause, a personalized evaluation may help determine whether estrogen replacement therapy is right for you.

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Why Estrogen Declines During Menopause

Menopause is diagnosed after a woman has gone 12 consecutive months without a menstrual period. However, hormonal changes often begin much earlier during perimenopause, typically starting in the late 30s or 40s.

Estrogen, which is mainly produced by the ovaries, begins to fluctuate and eventually decline as ovarian function slows. This decline is associated with a range of physical and emotional changes that many women find difficult to manage.

Potential Benefits of Estrogen Replacement Therapy 

Estrogen therapy is overseen by licensed medical professionals and tailored to each individual’s medical history, symptoms, and goals. While results vary, some women report improvements in the following areas:

Hot Flashes & Night Sweats

Hot flashes and night sweats are among the most common menopause-related symptoms. Estrogen therapy may help reduce their frequency and severity by supporting hormonal stability.

Sleep Quality

Some studies suggest that estrogen therapy may support more restful sleep by addressing nighttime symptoms and helping regulate systems that influence the sleep-wake cycle 1. Improved sleep may positively impact energy levels, mood, and daily resilience.

Mood & Emotional Wellbeing

Hormonal shifts may influence neurotransmitter function, which plays a role in mood and emotional regulation. Some women who begin estrogen therapy report improvements in mood stability and a reduction in feelings of irritability or emotional discomfort.

Sexual Comfort and Vaginal Health

Estrogen levels affect the vaginal tissues. As levels decline, some women experience dryness and discomfort during intimacy. Low-dose local estrogen therapy, when prescribed, may help support tissue hydration and elasticity.

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Estrogen Therapy and Areas of Ongoing Research

Bone Density

Estrogen plays a role in maintaining bone mass. After menopause, bone loss may accelerate. Some studies have shown that estrogen therapy can help support bone density and reduce fracture risk when part of a monitored care plan 2.

Cardiovascular and Metabolic Health

Estrogen has been associated with the regulation of cholesterol and vascular function. While estrogen therapy is not a treatment for heart disease, it may help support certain metabolic markers when used under medical supervision.

Muscle Mass and Body Composition

Estrogen helps influence fat distribution and muscle metabolism. As estrogen declines, some women notice increased midsection fat and decreased muscle tone. When paired with strength training and nutrition, estrogen therapy may support physical performance goals.

How Estrogen Replacement Therapy Works

The first step is a comprehensive evaluation conducted by a licensed healthcare provider. This may include symptom assessment, health history review, and lab testing when necessary. If estrogen therapy is determined to be appropriate, the provider will design a personalized plan tailored to the individual’s needs.

Many providers use bioidentical estrogen, which is chemically similar to the body’s naturally produced hormones. For women with an intact uterus, progesterone may also be prescribed to maintain hormonal balance.

Delivery Methods for Estrogen Therapy

Estrogen therapy is available in several forms. The delivery method prescribed will depend on individual factors and personal preferences.

  • Transdermal Patches: Provide steady absorption through the skin.
  • Topical Creams or Gels: Offer flexible application options and are absorbed through the skin.
  • Vaginal Tablets, Rings, or Creams: Typically used for local relief of vaginal symptoms.
  • Oral Tablets: A convenient method for some, though not appropriate for every patient.

A licensed healthcare provider will help determine the most suitable option based on your health status and treatment goals.

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Eden’s Role in Estrogen Therapy Access

Eden does not manufacture medications or provide medical treatment. Instead, we help simplify access to care by connecting you with experienced, licensed healthcare providers through a secure digital platform.

Here’s what to expect:

  • Expert Connection: Get matched with licensed healthcare providers who specialize in menopause and hormone-related care.
  • Personalized Prescriptions: If treatment is appropriate, your provider may prescribe medications through a state-licensed compounding pharmacy.
  • Home Delivery: Medications, when prescribed, are shipped discreetly to your door by our pharmacy partners.
  • Ongoing Monitoring: Your provider tracks progress and may adjust the treatment plan as needed to support your goals.

Take the First Step Toward Personalized Care

Menopause may bring challenges, but you don’t have to navigate them alone. If you’re looking for a more personalized and convenient way to explore estrogen replacement therapy, Eden can help.

Start your personalized hormone therapy evaluation with a licensed healthcare provider on the Eden platform today and explore whether estrogen therapy may be right for you.

Disclaimer: The FDA does not approve compounded medications for safety, quality, or manufacturing. Prescriptions and a medical evaluation are required for certain products. The information provided on this blog is for general informational purposes only. It is not intended as a substitute for professional advice from a qualified healthcare professional and should not be relied upon as personal health advice. The information contained in this blog is not meant to diagnose, treat, cure, or prevent any disease. Readers are advised to consult with a qualified healthcare professional for any medical concerns, including side effects. Use of this blog's information is at your own risk. The blog owner is not responsible for any adverse effects or consequences resulting from the use of any suggestions or information provided in this blog.

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References

  1. Cintron, D., Lahr, B. D., Bailey, K. R., Santoro, N., Lloyd, R., Manson, J. E., Neal-Perry, G., Pal, L., Taylor, H. S., Wharton, W., Naftolin, F., Harman, S. M., & Miller, V. M. (2017). Effects of oral versus transdermal menopausal hormone treatments on self-reported sleep domains and their association with vasomotor symptoms in recently menopausal women enrolled in the Kronos Early Estrogen Prevention Study (KEEPS). Menopause the Journal of the North American Menopause Society, 25(2), 145–153. https://doi.org/10.1097/gme.0000000000000971
  2. Levin, V. A., Jiang, X., & Kagan, R. (2018). Estrogen therapy for osteoporosis in the modern era. Osteoporosis International, 29(5), 1049–1055. https://doi.org/10.1007/s00198-018-4414-z