Does Semaglutide Cause Hair Loss? Exploring the Possible Connection

Does Semaglutide Cause Hair Loss?

Semaglutide (marketed as Wegovy®, Ozempic®, and Rybelsus®) has not been identified as a primary cause of hair loss in clinical trials. However, in the STEP studies, approximately 3% of participants receiving semaglutide for weight management reported hair shedding, compared to 1% in the placebo group.

Some researchers believe this may be related to telogen effluvium, a temporary hair shedding condition triggered by physical or metabolic stress, including significant weight loss. One study observed hair cycle changes in individuals with weight loss of 15% or more, suggesting that rapid weight loss, not the medication itself, may be a contributing factor.

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Can Weight Loss Trigger Hair Shedding?

Yes. Rapid or significant weight loss can shift hair follicles into a resting phase, leading to shedding 2–4 months later.

This is not unique to semaglutide. Any major calorie reduction or sudden weight change can contribute to this pattern. Some individuals experience regrowth within several months as hormone and nutrient levels stabilize, but outcomes can vary. Speak with a licensed provider if you have concerns about hair shedding during weight loss.

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Managing Hair Concerns While Using Semaglutide: What to Know

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If you're using semaglutide and are concerned about hair shedding, here are some provider-informed considerations to discuss:

1. Prioritize Protein

Adequate protein intake supports overall health, including normal hair growth. Some licensed providers recommend aiming for balanced protein sources such as:

• Poultry, fish, eggs
  
• Greek yogurt or dairy
  
• Legumes and soy
  
  

2. Eat Nutrient-Dense Foods

Key micronutrients for hair include:

• Iron, Zinc, Vitamin D
  
• Biotin and B-complex vitamins
  
  

Ask your provider about blood tests to assess for deficiencies.

3. Stay Hydrated

Water supports nutrient transport and cellular repair. Aim for 8+ glasses daily.

4. Reduce Stress

Chronic stress worsens hormonal imbalance. Try:

• Deep breathing or meditation
  
• Walking or gentle yoga
  
• Quality sleep habits
  
  

5. Use Gentle Hair Care

Avoid:

• Tight hairstyles and heavy brushing
  
• Excessive heat styling
  
• Sulfate-based shampoos
  
  

Opt for moisturizing, pH-balanced products.

6. Discuss Supplements with Your Provider

Targeted support may include:

• Biotin
  
• Vitamin D
  
• Collagen peptides
  
• Iron, if deficient
  
  

Avoid mega-doses unless guided by testing.

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Hair Shedding on Semaglutide? What to Track and Ask Your Provider

If you experience increased hair shedding while using semaglutide, consider the following steps to discuss with a licensed healthcare provider:

• Track the timing, duration, and severity of shedding
• Share your observations with your provider
• Ask whether nutritional screening or thyroid labs may be appropriate
• Always follow your provider’s guidance regarding treatment continuation or adjustments
• Some individuals report regrowth over time as weight and nutrient levels stabilize, but outcomes can vary

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Final Thoughts

Does semaglutide cause hair loss? Hair loss is not considered a direct side effect of semaglutide in clinical trials, but some individuals may experience temporary shedding related to rapid weight loss, a known trigger for telogen effluvium.

In many cases, hair regrowth has been observed over time as the body adapts. Maintaining adequate nutrition, hydration, stress management, and working closely with a licensed provider may help support overall health, including hair health, during GLP-1 treatment.

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Disclaimer

This article is for general educational purposes and is not a substitute for medical advice. Always speak with a qualified provider before altering your treatment or supplement routine. Eden does not prescribe, compound, or manufacture medications. All care is delivered through licensed healthcare professionals.

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