Hair shedding has been reported during weight loss, but is semaglutide the cause? Learn what current research suggests and when to speak with your provider about hair health on GLP-1 medications.
With increasing use of GLP-1 receptor agonists like semaglutide for weight management and type 2 diabetes, concerns about possible side effects, including hair loss, have grown.
While hair loss is not identified as a primary side effect of semaglutide in clinical trials, some users have reported temporary hair shedding, especially during periods of significant weight change. This may align with a condition known as telogen effluvium, which can occur after physical or emotional stress, including weight loss.
This article reviews current research and observations related to semaglutide and hair shedding, the potential role of weight changes, and general tips individuals can discuss with a licensed provider to support overall hair health.
Please note: This article is for informational purposes only and is not intended as medical advice. Always consult a licensed healthcare provider for guidance specific to your needs.
Semaglutide (marketed as Wegovy®, Ozempic®, and Rybelsus®) has not been identified as a primary cause of hair loss in clinical trials. However, in the STEP studies, approximately 3% of participants receiving semaglutide for weight management reported hair shedding, compared to 1% in the placebo group.
Some researchers believe this may be related to telogen effluvium, a temporary hair shedding condition triggered by physical or metabolic stress, including significant weight loss. One study observed hair cycle changes in individuals with weight loss of 15% or more, suggesting that rapid weight loss, not the medication itself, may be a contributing factor.
Yes. Rapid or significant weight loss can shift hair follicles into a resting phase, leading to shedding 2–4 months later.
This is not unique to semaglutide. Any major calorie reduction or sudden weight change can contribute to this pattern. Some individuals experience regrowth within several months as hormone and nutrient levels stabilize, but outcomes can vary. Speak with a licensed provider if you have concerns about hair shedding during weight loss.
If you're using semaglutide and are concerned about hair shedding, here are some provider-informed considerations to discuss:
1. Prioritize Protein
Adequate protein intake supports overall health, including normal hair growth. Some licensed providers recommend aiming for balanced protein sources such as:
Key micronutrients for hair include:
Ask your provider about blood tests to assess for deficiencies.
Water supports nutrient transport and cellular repair. Aim for 8+ glasses daily.
Chronic stress worsens hormonal imbalance. Try:
Avoid:
Opt for moisturizing, pH-balanced products.
Targeted support may include:
Avoid mega-doses unless guided by testing.
If you experience increased hair shedding while using semaglutide, consider the following steps to discuss with a licensed healthcare provider:
Does semaglutide cause hair loss? Hair loss is not considered a direct side effect of semaglutide in clinical trials, but some individuals may experience temporary shedding related to rapid weight loss, a known trigger for telogen effluvium.
In many cases, hair regrowth has been observed over time as the body adapts. Maintaining adequate nutrition, hydration, stress management, and working closely with a licensed provider may help support overall health, including hair health, during GLP-1 treatment.
This article is for general educational purposes and is not a substitute for medical advice. Always speak with a qualified provider before altering your treatment or supplement routine. Eden does not prescribe, compound, or manufacture medications. All care is delivered through licensed healthcare professionals.
Disclaimer: The FDA does not approve compounded medications for safety, quality, or manufacturing. Prescriptions and a medical evaluation are required for certain products. The information provided on this blog is for general informational purposes only. It is not intended as a substitute for professional advice from a qualified healthcare professional and should not be relied upon as personal health advice. The information contained in this blog is not meant to diagnose, treat, cure, or prevent any disease. Readers are advised to consult with a qualified healthcare professional for any medical concerns, including side effects. Use of this blog's information is at your own risk. The blog owner is not responsible for any adverse effects or consequences resulting from the use of any suggestions or information provided in this blog.
Hair loss is not listed as a common side effect in clinical trials, but approximately 3% of participants in weight management studies reported temporary shedding. This may be related to rapid weight loss rather than the medication itself.
Some individuals may experience regrowth if the shedding is due to telogen effluvium, a temporary condition triggered by stress or weight loss. Outcomes can vary.
There are no guaranteed prevention methods, but maintaining balanced nutrition, adequate protein, hydration, and stress management may support overall hair health. Speak with your provider about possible lab testing or supplements.
Always consult your provider before making any changes to your treatment. They can help assess potential causes and recommend appropriate next steps.
Yes. Thyroid issues, anemia, or stress may also contribute to hair loss. Medical evaluation is important.
