Does Semaglutide Cause Hair Loss? Understanding the Connection

Does Semaglutide Cause Hair Loss?

Semaglutide (marketed as Wegovy®, Ozempic®, and Rybelsus®) is not strongly linked to hair loss in most clinical trials. However, in the STEP trials, about 3% of patients taking semaglutide for weight loss reported hair loss, compared to 1% in the placebo group.

This pattern suggests a connection to telogen effluvium. This is a temporary condition triggered by physical or metabolic stress, such as rapid weight loss. A recent study confirmed this link, finding that even a 15% weight loss can trigger this hair cycle disruption.

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Can Weight Loss Trigger Hair Shedding?

Yes. Rapid or significant weight loss can shift hair follicles into a resting phase, leading to shedding 2–4 months later.

This is not unique to semaglutide. Any intensive calorie reduction or sudden weight change can result in telogen effluvium. Affected individuals usually see regrowth within 6 months as hormone and nutrient levels rebalance.

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How to Minimize Hair Loss During Semaglutide Treatment

If you're using semaglutide and concerned about shedding, try these steps:

1. Prioritize Protein

Protein is critical for hair follicle function. Aim for 25–30 grams per meal from:

• Poultry, fish, eggs
  
  
• Greek yogurt or dairy
  
  
• Legumes and soy
  
  

2. Eat Nutrient-Dense Foods

Key micronutrients for hair include:

• Iron, Zinc, Vitamin D
  
  
• Biotin and B-complex vitamins
  
  

Ask your provider about blood tests to assess for deficiencies.

3. Stay Hydrated

Water supports nutrient transport and cellular repair. Aim for 8+ glasses daily.

4. Reduce Stress

Chronic stress worsens hormonal imbalance. Try:

• Deep breathing or meditation
  
• Walking or gentle yoga
  
• Quality sleep habits
  
  

5. Use Gentle Hair Care

Avoid:

• Tight hairstyles and heavy brushing
  
• Excessive heat styling
  
• Sulfate-based shampoos
  
  

Opt for moisturizing, pH-balanced products.

6. Discuss Supplements with Your Provider

Targeted support may include:

• Biotin
  
• Vitamin D
  
• Collagen peptides
  
• Iron, if deficient
  
  

Avoid mega-doses unless guided by testing.

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What to Do If You Notice Hair Shedding

If you see increased hair fall while using semaglutide:

• Track onset, duration, and severity
  
• Inform your provider
  
• Ask about nutritional screening or thyroid labs
  
• Continue treatment unless advised otherwise
  
  

Most patients will experience natural regrowth as their weight and nutrient balance stabilizes.

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Final Thoughts

Does semaglutide cause hair loss? Not directly, but rapid weight loss during treatment may trigger telogen effluvium, a temporary and reversible form of shedding.

The good news is that hair typically regrows as your body adjusts. With the right support, nutrition, hydration, stress management, and medical supervision, you can maintain hair health while achieving your metabolic goals with semaglutide.

Disclaimer

This article is for general educational purposes and is not a substitute for medical advice. Always speak with a qualified provider before altering your treatment or supplement routine. Eden does not prescribe, compound, or manufacture medications. All care is delivered through licensed healthcare professionals.

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