Getting Started

Call your primary doctor if you have side effects that concern you, or you suspect a drug allergy has occurred. If your symptoms are severe, seek medical help immediately. If you experience any side effects listed in the section below, seek medical help immediately.

In case you missed it..

Call your primary doctor if you have side effects that concern you, or you suspect a drug allergy has occurred. If your symptoms are severe, seek medical help immediately. If you experience any side effects listed in the section below, seek medical help immediately.

See a complete list of side-effects here.

Special considerations:‍

• Must take upon waking in the mornings.
• Taking with any food, beverages, or other medications can reduce the effectiveness of this drug and alter the absorption of any other drugs.
• Do not take with Levothyroxine or any other medications with a narrow therapeutic index. Separate at least 30 minutes from this or any other medications. ‍
• If you are on Levothyroxine, or any other medications with a narrow therapeutic index, such as aminoglycosides, ciclosporin, carbamazepine, digoxin, digitoxin, flecainide, lithium, phenytoin, phenobarbital, rifampicin, theophylline or warfarin—speak with your doctor to see if this medication may be right for you.

‍Most common side effects include:

• ‍‍Nausea
• Stomach (abdominal) pain
• Diarrhea
• Vomiting
• Decreased appetite
• Constipation

‍See a complete list of side-effects here.

‍Do not use if you have been diagnosed with the following:

• Diabetic ketoacidosis
• Type 1 diabetes
• Diabetic retinopathy
• Kidney disease
• Multiple endocrine neoplasia syndrome type 2 (MEN 2)
• Thyroid cancer
• Pancreatitis

SEMAGLUTIDE WARNING

• Please contact your doctor ASAP and seek in-person care immediately if a side effect becomes problematic or you experience:
  Severe nausea and/or vomiting resulting in dehydration—it is important to stay well hydrated and drink plenty of fluids while on this medication.
• Kidney problems/kidney failure:
  • vomiting, nausea, diarrhea can cause dehydration and kidney issues and make kidney problems worse in individuals who have pre-existing kidney conditions; may sometimes lead to the need for hemodialysis.
• Thyroid C-Cell Tumor:
  • Trouble swallowing, hoarseness, a lump or swelling in your neck, or shortness of breath (see black box warning below).
• Pancreatitis:
  • Severe pain in your abdomen or back that will not go away.
• Acute gallbladder disease:
  • Pain in the middle or right upper stomach, fever, white parts of your eyes turn yellow or skin turns yellow, nausea/vomiting. If gallstones or inflammation of the gallbladder is suspected further studies are needed.
• Hepatitis/Elevated liver enzymes/Jaundice.
• Diabetic retinopathy problems: Changes in vision in those with type II diabetes, particularly vision problems may worsen in those with a history of diabetic retinopathy.
• Severe gastrointestinal disease—may cause gastrointestinal disease; do not use if you have a history of severe gastrointestinal disease.
• Signs of low blood sugar (for example, dizziness, weakness, shakiness, jitteriness, headache, anxiety/mood changes, rapid heartbeat, confusion, slurred speech, sweating, or lightheadedness). While this is rare with GLP-1s, if it occurs, please seek in-person care immediately. If you have these symptoms, try having liquid or food containing sugar (around 15-20 grams)—drinking juice, having regular soda, or eating some hard candies right away, as this will help raise your blood sugar quickly. If taken with insulin or an insulin secretagogue (ie sulfonylurea) it is best to talk to your healthcare provider about possibly lowering the dose of these medications to lower the risk of hypoglycemia.
• Increasing heart rate.
• Worsening depression, behavior changes, or suicidality.
• Never share your autoinjector pens with other people.

‍Note: The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.